Lisinopril HCTZ is a combo of antihypertensive agent.
- Lisinopril is one of the most well-known and well-studied ACE inhibitors.
- HCTZ (Hydrochlorothiazide) is a thiazide diuretic (reduces blood volume).
The drug provides effective lowering of pressure in the blood vessels, and reduces their peripheral vascular resistance. It is prescribed for the treatment of patients suffering from mild or moderate hypertension.
Key information about Lisinopril HCTZ:
- Dosage forms: tablets.
- Dosage strength: 10/12.5 mg, 20/12.5 mg and 20/25 mg.
- Package size: 10-90 tablets.
Lisinopril HCTZ provides an antihypertensive effect. The following effects are achieved through this:
- A decrease in pressure in the lungs capillaries take place.
- Patient’s blood pressure lowers to an acceptable level.
- The volume of blood pumped by the heart per minute increases.
- Hypertrophy of the heart muscle and arterial walls reduces.
Recommended Dosing Schedule
When you buy Lisinopril HCTZ, you will find instructions for use in the package. It describes quite fully the main aspects of the drug use. Here, we will list only the most important details:
- The usual dosage is one tablet, administered once a day.
- Better make a 24-hour break between the doses.
- The dose can be increased to two pills, administered at a time.
Lisinopril HCTZ reviews indicate that the maximum effect of the drug manifests within 14-28 days of continuous treatment. If you interrupt treatment or reduce the dosage without consulting a specialist, your blood pressure is very likely to rise again.
For older people, Lisinopril HCTZ dosage adjustment is not required. The drug is not intended for the treatment of hypertension in children. It should not be used during lactation and pregnancy.
General precautions for use and unfavorable reactions
Side effects during the use of Lisinopril HCTZ are similar to the side effects, caused by the administration of other ACE inhibitors + thiazide diuretic. However, the frequency of these effects differ.
Examples of side effects of Lisinopril HCTZ:
- Fainting
- Hypoglycemia
- Dizziness
- Abdominal discomfort
- Erectile dysfunction
- Renal dysfunction
- Lack of energy and strength.
Should these or any other side effects manifest, stop taking the drug and consult a doctor.
Overdose with this drug can cause a severe drop of blood pressure and tachycardia. To eliminate the effects of overdose, you need to have gastric irrigation and take activated charcoal.
During the treatment course, it is recommended to completely abandon alcohol. This is because simultaneous use of the drug and alcohol unpredictably enhances the hypotensive effect. Possible consequences are tachycardia, bradycardia, acute cardiac failure and syncope.
Lisinopril HCTZ in the international market
Zestoretic is the brand name for Lisinopril HCTZ. The drug was first introduced in the US market in 1989 after it was approved by the FDA.
Lisinopril HCTZ cost in the US is not very high. This results from the fact that the drug has been on the market for a long time already. A variety of generic Lisinopril HCTZ versions are available for sale, as well. Their presence improves competition in the market and provides consumers with additional options for choosing the preferred drug.
American suppliers of Lisinopril HCTZ are such companies, as:
- Sun
- Ivax
- Watson
- Sandoz
- Prinston
- Lupin
- Aurobindo.
If antihypertensive drugs are too expensive, you can order cheap Lisinopril HCTZ online. The drug will be delivered in discrete packaging to the threshold of your home or at any specified address.